Di Domenico, F., Tramutola, A., Barone, E., Lanzillotta, C., Defever, O., Arena, A., … Perluigi, M. (2019). Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome. Redox Biology, 23, 101162. https://doi.org/10.1016/j.redox.2019.101162

Sharma, N., Tramutola, A., Lanzillotta, C., Arena, A., Blarzino, C., Cassano, T., … Barone, E. (2019). Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer’s disease. Neurobiology of Disease, 125, 176-189. https://doi.org/10.1016/j.nbd.2019.02.003

Tramutola, A., Lanzillotta, C., Barone, E., Arena, A., Zuliani, I., Mosca, L., … Di Domenico, F. Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome. Translational Neurodegeneration, 7, 28. https://doi.org/10.1186/s40035-018-0133-9 (Original work published 2018)

Di Domenico, F., Pupo, G., Mancuso, C., Barone, E., Paolini, F., Arena, A., … Perluigi, M. Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer’s disease. Journal of Alzheimer’s Disease : JAD, 44(4), 1107-20. https://doi.org/10.3233/JAD-141254 (Original work published 2015)

Barone, E., Arena, A., Head, E., Butterfield, D., & Perluigi, M. (2018). Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism. Free Radical Biology & Medicine, 114, 84-93. https://doi.org/10.1016/j.freeradbiomed.2017.07.009

Tramutola, A., Pupo, G., Di Domenico, F., Barone, E., Arena, A., Lanzillotta, C., … Perluigi, M. Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. Journal of Alzheimer’s Disease : JAD, 52(1), 359-371. https://doi.org/10.3233/JAD-151105 (Original work published 2016)

Barone, E., Di Domenico, F., Cassano, T., Arena, A., Tramutola, A., Lavecchia, M., … Perluigi, M. (2016). Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. Free Radical Biology & Medicine, 91, 127-42. https://doi.org/10.1016/j.freeradbiomed.2015.12.012

Tramutola, A., Arena, A., Cini, C., Butterfield, D., & Barone, E. (2017). Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology. Expert Review of Neurotherapeutics, 17(1), 59-75. https://doi.org/10.1080/14737175.2017.1246183

Tramutola, A., Di Domenico, F., Barone, E., Arena, A., Giorgi, A., di Francesco, L., … Perluigi, M. (2017). Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology. Antioxidants & Redox Signaling, 26(7), 280-298. https://doi.org/10.1089/ars.2016.6686 (Original work published 2017)